Product Description

Wockhardt Cough Syrup

Wockhardt Cough Syrup is a prescription medication containing promethazine hydrochloride (an antihistamine) and codeine phosphate (an opioid cough suppressant). It is manufactured by Wockhardt and is indicated for the temporary relief of cough and upper respiratory symptoms associated with allergies or the common cold in adults 18 years and older.

Composition (Typical Formulation)

Each 5 mL (one teaspoon) typically contains:

• Codeine phosphate: 10 mg
• Promethazine hydrochloride: 6.25 mg
• Often includes alcohol (around 7%) and a flavored syrup base.

It is classified as a Schedule V controlled substance in the United States due to the presence of codeine.

Pharmacology

• Codeine: Acts on opioid receptors in the brain to suppress the cough reflex. It also provides mild analgesic and sedative effects.
• Promethazine: An antihistamine that helps reduce allergy symptoms (runny nose, sneezing) and adds significant sedative properties.

The combination produces cough relief along with drowsiness and relaxation.

Safety Profile & Risks

When used exactly as prescribed for short-term medical purposes, the medication can be effective. However, it carries serious risks:

Common Side Effects:

• Drowsiness and sedation
• Dizziness
• Dry mouth
• Constipation
• Nausea

Serious Risks:

• Respiratory depression (slowed or dangerous breathing) — can be life-threatening, especially in children, elderly, or when combined with other sedatives.
• Addiction and dependence — Codeine is an opioid with high abuse potential.
• Overdose: Symptoms include extreme drowsiness, confusion, slow breathing, coma, and death.
• Ultra-rapid metabolizers of codeine (due to CYP2D6 genetics) can convert it to morphine too quickly, increasing toxicity risk.
• Severe sedation when mixed with alcohol, benzodiazepines, other opioids, or muscle relaxants.

Abuse Potential

Wockhardt Cough Syrup (and similar promethazine-codeine products) has a well-documented history of recreational abuse, often referred to as “lean,” “purple drank,” or “sizzurp” when mixed with soda and candy. This practice significantly increases the risk of overdose, respiratory failure, and death.

Contraindications

• Children under 18 (FDA black box warning)
• History of opioid addiction or respiratory issues
• Pregnancy (can cause neonatal opioid withdrawal)
• Concurrent use with other CNS depressants

Important Note: This is a neutral, educational overview based on FDA labeling and medical sources. Wockhardt Cough Syrup is a controlled prescription medication with significant risks of misuse, addiction, and overdose. This information does not encourage use. Only take it exactly as prescribed by a licensed healthcare provider.