{"id":7736,"date":"2026-04-09T10:15:59","date_gmt":"2026-04-09T10:15:59","guid":{"rendered":"https:\/\/trusthillpharmacy.de\/?post_type=product&#038;p=7736"},"modified":"2026-04-14T16:02:12","modified_gmt":"2026-04-14T16:02:12","slug":"co-codamol-15-500-mg","status":"publish","type":"product","link":"https:\/\/trusthillpharmacy.de\/de\/shop\/co-codamol-15-500-mg\/","title":{"rendered":"Co-Codamol 15\/500 mg"},"content":{"rendered":"<h1><a href=\"http:\/\/google.com\">Co-Codamol 15\/500 mg<\/a><\/h1>\n<div class=\"prose break-words dark:prose-invert prose-p:leading-relaxed prose-pre:p-0 fix-max-with-100 prose-p:!mt-0\">\n<p class=\"mb-2 last:mb-0\"><strong>Was es ist:<\/strong><br \/>\n<a href=\"https:\/\/trusthillpharmacy.de\/de\/\">Co-Codamol<\/a> 15\/500 mg ist ein Kombinationsschmerzmittel, das Folgendes enth\u00e4lt:<\/p>\n<ul>\n<li><strong>Codeinphosphat<\/strong>: 15 mg (ein Opioid-Analgetikum, das durch Bindung an Opioidrezeptoren im Gehirn wirkt, um die Schmerzwahrnehmung zu verringern).<\/li>\n<li><strong>Paracetamol (Acetaminophen)<\/strong>: 500 mg (ein nicht-opioides Schmerzmittel und Fiebermittel, das die Prostaglandinsynthese im zentralen Nervensystem hemmt).<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\">Es handelt sich hierbei um eine niedrigere Dosierung (Co-Codamol 15\/500 mg) im Vergleich zu h\u00f6heren Dosierungen wie 30\/500 oder 8\/500 mg. In einigen L\u00e4ndern (z. B. Gro\u00dfbritannien) ist es rezeptfrei in begrenzten Packungsgr\u00f6\u00dfen erh\u00e4ltlich, st\u00e4rkere Dosierungen sind jedoch verschreibungspflichtig.<\/p>\n<p class=\"mb-2 last:mb-0\"><strong>\u00dcbliche Anwendungsgebiete:<\/strong><\/p>\n<ul>\n<li>Linderung leichter bis m\u00e4\u00dfiger Schmerzen (z. B. Kopfschmerzen, Zahnschmerzen, Muskelschmerzen, Regelschmerzen, Muskelkater nach Verletzungen).<\/li>\n<li>Nur zur kurzfristigen Anwendung (in der Regel maximal 3 Tage bei codeinhaltigen Produkten, um eine Abh\u00e4ngigkeit zu vermeiden).<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\"><strong>Evidenz und Wirksamkeit:<\/strong><\/p>\n<ul>\n<li>Unterst\u00fctzt durch NHS-Richtlinien und Studien in\u00a0<em>The Lancet<\/em>\u00a0(z. B. bieten Codein-Paracetamol-Kombinationen eine bessere Schmerzlinderung als Paracetamol allein bei akuten Schmerzen, mit einer NNT von ca. 4 f\u00fcr eine 50%ige Schmerzlinderung \u2013 McQuay et al., Metaanalysen aus den 1990er Jahren).<\/li>\n<li>Co-Codamol 15\/500 mg wird \u00fcber das CYP2D6-Enzym zu Morphin metabolisiert; etwa 10 % der Menschen sind langsame Metabolisierer und profitieren daher weniger stark (FDA weist in einem Warnhinweis auf diese Variabilit\u00e4t hin).<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\"><strong>Dosierung (Erwachsene):<\/strong><\/p>\n<\/div>\n<div class=\"overflow-x-auto my-4\">\n<table class=\"markdown-table\">\n<thead>\n<tr>\n<th>Alter Gruppe<\/th>\n<th>Maximale Tagesdosis<\/th>\n<th>Notes<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Erwachsene (ab 16 Jahren)<\/td>\n<td>8 Tabletten (120 mg Codein \/ 4 g Paracetamol)<\/td>\n<td>1-2 Tabletten alle 4-6 Stunden; die empfohlene Tagesdosis darf nicht \u00fcberschritten werden.<\/td>\n<\/tr>\n<tr>\n<td>Kinder (12-15)<\/td>\n<td>1 Tablette alle 6 Stunden (maximal 4 pro Tag)<\/td>\n<td>Nicht f\u00fcr Kinder unter 12 Jahren.<\/td>\n<\/tr>\n<tr>\n<td>Leberprobleme bei \u00e4lteren Menschen<\/td>\n<td>Dosis reduzieren<\/td>\n<td>Konsultieren Sie einen Arzt.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<div class=\"prose break-words dark:prose-invert prose-p:leading-relaxed prose-pre:p-0 fix-max-with-100 prose-p:!mt-0\">\n<p class=\"mb-2 last:mb-0\"><strong>Nebenwirkungen:<\/strong><\/p>\n<ul>\n<li><strong>Common<\/strong>Schl\u00e4frigkeit, Schwindel, Verstopfung, \u00dcbelkeit (codeinbedingt); H\u00e4ufigkeit in klinischen Studien ca. 20-30%.<\/li>\n<li><strong>Ernst<\/strong>: Atemdepression (selten bei niedrigen Dosen), Suchtrisiko (Codein ist ein kontrollierter Stoff), Paracetamol-\u00dcberdosierung \u2192 Leberversagen (toxischer Metabolit NAPQI \u00fcberlastet die Glutathionspeicher; Risiko &gt;4 g\/Tag laut MHRA).<\/li>\n<li><strong>Allergisch<\/strong>Ausschlag, Schwellung.<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\"><strong>Warnungen und Interaktionen:<\/strong><\/p>\n<ul>\n<li><strong>Nicht kombinieren mit<\/strong>: Alkohol, andere Opioide, Beruhigungsmittel (erh\u00f6ht das Risiko einer \u00dcberdosierung \u2013 siehe Opioid-Richtlinien der CDC).<\/li>\n<li><strong>Vermeiden Sie es, wenn<\/strong>Schwangerschaft\/Stillzeit (Codein geht in die Muttermilch \u00fcber), Asthma, Leber-\/Nierenerkrankung oder Suchterkrankung in der Vorgeschichte.<\/li>\n<li><strong>Anzeichen einer \u00dcberdosis<\/strong>: Erbrechen, stecknadelkopfgro\u00dfe Pupillen, Koma \u2013 sofort not\u00e4rztliche Hilfe hinzuziehen (Naloxon bei Codein; N-Acetylcystein bei Paracetamol).<\/li>\n<li>Die britische Arzneimittelbeh\u00f6rde MHRA r\u00e4t aufgrund des Risikos von Apnoe von der Anwendung von Codein bei Kindern unter 12 Jahren ab (Urteil aus dem Jahr 2013, basierend auf Daten der Arzneimittelsicherheit).<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\"><strong>Verf\u00fcgbarkeit:<\/strong><\/p>\n<ul>\n<li>In Gro\u00dfbritannien: Rezeptfrei in Apotheken erh\u00e4ltlich (maximal 16 Tabletten\/Packung); gr\u00f6\u00dfere Mengen auf Rezept.<\/li>\n<li>USA: Entspricht Tylenol Nr. 2 (\u00e4hnliche St\u00e4rke); Codein ist verschreibungspflichtig.<\/li>\n<li>Beachten Sie stets die \u00f6rtlichen Bestimmungen.<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\">Dies sind allgemeine Informationen aus Quellen wie BNF, NHS, EMA und FDA-Etiketten \u2013\u00a0<strong>Dies ist keine medizinische Beratung.<\/strong>Konsultieren Sie vor der pers\u00f6nlichen Anwendung von Co-Codamol 15\/500 mg einen Arzt oder Apotheker, insbesondere wenn Sie gesundheitliche Probleme haben oder andere Medikamente einnehmen. Beschreiben Sie Ihre Schmerzen, um eine individuelle Beratung zu erhalten.<\/p>\n<\/div>\n\n    <div class=\"xs_social_share_widget xs_share_url after_content \t\tmain_content  wslu-style-1 wslu-share-box-shaped wslu-fill-colored wslu-none wslu-share-horizontal wslu-theme-font-no wslu-main_content\">\n\n\t\t\n        <ul>\n\t\t\t        <\/ul>\n    <\/div>","protected":false},"excerpt":{"rendered":"<p>Co-Codamol 15\/500mg What it is: Co-Codamol 15\/500mg is a combination painkiller containing: Codeine phosphate: 15 mg (an opioid analgesic that works by binding to opioid receptors in the brain to reduce pain perception). Paracetamol (acetaminophen): 500 mg (a non-opioid pain reliever and fever reducer that inhibits prostaglandin synthesis in the central nervous system). This is &hellip; <a href=\"https:\/\/trusthillpharmacy.de\/de\/shop\/co-codamol-15-500-mg\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Co-Codamol 15\/500 mg<\/span><\/a><\/p>","protected":false},"featured_media":7749,"comment_status":"closed","ping_status":"closed","template":"","meta":{"postBodyCss":"","postBodyMargin":[],"postBodyPadding":[],"postBodyBackground":{"backgroundType":"classic","gradient":""}},"product_brand":[],"product_cat":[108],"product_tag":[211],"class_list":["post-7736","product","type-product","status-publish","has-post-thumbnail","product_cat-pain-relief","product_tag-co-codamol-15-500mg","instock","shipping-taxable","purchasable","product-type-variable"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.5 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Co-Codamol 15\/500mg - Trusthill Pharmacy<\/title>\n<meta name=\"description\" content=\"Co-Codamol 15\/500mg is a a non-opioid pain reliever and fever reducer that inhibits prostaglandin synthesis in the central nervous system\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/trusthillpharmacy.de\/de\/shop\/co-codamol-15-500-mg\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Co-Codamol 15\/500mg\" \/>\n<meta property=\"og:description\" content=\"Co-Codamol 15\/500mg is a a non-opioid pain reliever and fever reducer that inhibits prostaglandin synthesis in the central nervous system\" \/>\n<meta property=\"og:url\" content=\"https:\/\/trusthillpharmacy.de\/de\/shop\/co-codamol-15-500-mg\/\" \/>\n<meta property=\"og:site_name\" content=\"Trusthill Pharmacy\" \/>\n<meta property=\"article:modified_time\" content=\"2026-04-14T16:02:12+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/trusthillpharmacy.de\/wp-content\/uploads\/2026\/04\/photo_5096273778597104775_x.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"500\" \/>\n\t<meta property=\"og:image:height\" content=\"500\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Gesch\u00e4tzte Lesezeit\" \/>\n\t<meta name=\"twitter:data1\" content=\"2\u00a0Minuten\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/trusthillpharmacy.de\\\/shop\\\/co-codamol-15-500mg\\\/\",\"url\":\"https:\\\/\\\/trusthillpharmacy.de\\\/shop\\\/co-codamol-15-500mg\\\/\",\"name\":\"Co-Codamol 15\\\/500mg - 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