{"id":8018,"date":"2026-04-22T22:20:32","date_gmt":"2026-04-22T22:20:32","guid":{"rendered":"https:\/\/trusthillpharmacy.de\/?post_type=product&#038;p=8018"},"modified":"2026-04-24T00:16:16","modified_gmt":"2026-04-24T00:16:16","slug":"tramadol-200-mg","status":"publish","type":"product","link":"https:\/\/trusthillpharmacy.de\/de\/shop\/tramadol-200-mg\/","title":{"rendered":"Tramadol 200 mg"},"content":{"rendered":"<h1><a href=\"http:\/\/google.com\">Tramadol 200 mg<\/a><\/h1>\n<div class=\"prose break-words dark:prose-invert prose-p:leading-relaxed prose-pre:p-0 fix-max-with-100 prose-p:!mt-0\">\n<p class=\"mb-2 last:mb-0\"><a href=\"https:\/\/trusthillpharmacy.de\/de\/\">Tramadol 200 mg<\/a> Es handelt sich um ein synthetisches Opioid-Analgetikum zur Behandlung von m\u00e4\u00dfigen bis m\u00e4\u00dfig starken Schmerzen. Die 200-mg-Dosis ist eine h\u00f6her dosierte Retardformulierung, die typischerweise zur kontinuierlichen Schmerztherapie und nicht zur bedarfsweisen Anwendung verschrieben wird. Im Folgenden finden Sie eine sachliche Aufschl\u00fcsselung basierend auf etablierten medizinischen Quellen wie der FDA, der EMA und pharmakologischen Nachschlagewerken (z. B. Lexicomp, Micromedex):<\/p>\n<h4>Wichtigste Fakten<\/h4>\n<\/div>\n<div class=\"overflow-x-auto my-4\">\n<table class=\"markdown-table\">\n<thead>\n<tr>\n<th>Aspekt<\/th>\n<th>Details<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Generic Name<\/td>\n<td>Tramadolhydrochlorid<\/td>\n<\/tr>\n<tr>\n<td>Form<\/td>\n<td>Retardtablette (200 mg); gibt den Wirkstoff langsam \u00fcber 24 Stunden ab<\/td>\n<\/tr>\n<tr>\n<td>Allgemeine Markennamen<\/td>\n<td>Ultram ER, ConZip (oder Generika)<\/td>\n<\/tr>\n<tr>\n<td>Verwendung<\/td>\n<td>Chronische Schmerzen (z. B. Arthrose, neuropathische Schmerzen); nicht f\u00fcr akute\/postoperative Schmerzen in der Notaufnahme.<\/td>\n<\/tr>\n<tr>\n<td>Mechanismus<\/td>\n<td>Schwacher \u03bc-Opioidrezeptor-Agonist + Serotonin-\/Noradrenalin-Wiederaufnahmehemmer (SNRI)<\/td>\n<\/tr>\n<tr>\n<td>Beginn\/Dauer<\/td>\n<td>Wirkungseintritt: 1\u20132 Stunden; Wirkungsmaximum: 4\u20136 Stunden; Wirkungsdauer: ca. 24 Stunden<\/td>\n<\/tr>\n<tr>\n<td>Standarddosierung<\/td>\n<td>Erwachsene: Beginnen Sie mit 100\u2013200 mg einmal t\u00e4glich; maximal 400 mg\/Tag. Die Dosis ist an Alter, Nieren- und Leberfunktion anzupassen.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<div class=\"prose break-words dark:prose-invert prose-p:leading-relaxed prose-pre:p-0 fix-max-with-100 prose-p:!mt-0\">\n<h4>Wirksamkeitsnachweise<\/h4>\n<ul>\n<li><strong>Klinische Studien<\/strong>Studien (z. B. FDA-Zulassungsdaten f\u00fcr Ultram ER) zeigten, dass 200 mg t\u00e4glich die Schmerzwerte bei Patienten mit chronischen Schmerzen um 30\u201350 % im Vergleich zu Placebo reduzierten (z. B. Studien zu R\u00fcckenschmerzen mit mehr als 1.000 Teilnehmern). Die Wirkung ist vergleichbar mit der anderer Opioide wie Oxycodon in \u00e4quipotenten Dosen, jedoch mit geringerer Atemdepression.<\/li>\n<li><strong>Meta-Analysen<\/strong>Cochrane Reviews (2020) best\u00e4tigen eine moderate Wirksamkeit bei neuropathischen Schmerzen (NNT=4,7 f\u00fcr eine Schmerzlinderung von 30 %), allerdings ist die Wirksamkeit bei starken Schmerzen st\u00e4rkeren Opioiden unterlegen.<\/li>\n<li><strong>Einschr\u00e4nkungen<\/strong>Bei 20-30 % der Langzeitnutzer entwickelt sich eine Toleranz; aufgrund des Missbrauchspotenzials nicht als Mittel der ersten Wahl eingesetzt.<\/li>\n<\/ul>\n<h4>Nebenwirkungen (h\u00e4ufig &gt;5 %)<\/h4>\n<ul>\n<li>\u00dcbelkeit\/Erbrechen (20-40 %)<\/li>\n<li>Schwindel\/Schl\u00e4frigkeit (15-30%)<\/li>\n<li>Verstopfung (10-20%)<\/li>\n<li>Kopfschmerzen, trockener Mund<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\"><strong>Ernsthafte Risiken<\/strong>\u00a0(1-5% Inzidenz):<\/p>\n<ul>\n<li><strong>Serotonin-Syndrom<\/strong>Risiken bei der Einnahme von SSRIs\/SNRIs (Symptome: Unruhe, Hyperthermie, Krampfanf\u00e4lle). Fallberichte zeigen ein Risiko von 1:1000.<\/li>\n<li><strong>Anf\u00e4lle<\/strong>Dosisabh\u00e4ngig (0,1-1 % bei &gt;300 mg\/Tag); h\u00f6her bei Epileptikern oder bei Tramadol-\u00dcberdosierung.<\/li>\n<li><strong>Atemdepression<\/strong>Bei therapeutischen Dosen selten, bei \u00dcberdosierung jedoch t\u00f6dlich (bindet schwach an \u03bc-Rezeptoren, LD50 ~500 mg\/kg bei Tieren).<\/li>\n<li><strong>Hypogonadismus<\/strong>Chronischer Gebrauch unterdr\u00fcckt den Testosteronspiegel (Studien zeigen einen R\u00fcckgang von 20-50%).<\/li>\n<li><strong>Abh\u00e4ngigkeit\/Entzug<\/strong>: Gem\u00e4\u00df DSM-5 wird dies als Risiko f\u00fcr eine Opioidkonsumst\u00f6rung eingestuft; Entzugssymptome \u00e4hneln einer Grippe und Angstzust\u00e4nden (Inzidenz 10-15% bei &gt;3 Monaten Konsum).<\/li>\n<\/ul>\n<h4>Gegenanzeigen &amp; Warnhinweise<\/h4>\n<ul>\n<li><strong>Vermeiden Sie in<\/strong>: Children &lt;12, post-op in kids &lt;18 (FDA black box for respiratory risk), acute intoxication, severe respiratory depression.<\/li>\n<li><strong>Arzneimittelwechselwirkungen<\/strong>MAO-Hemmer (innerhalb von 14 Tagen), SSRIs (Serotonin-Syndrom), CYP2D6-Hemmer (z. B. verdoppelt Fluoxetin die Exposition).<\/li>\n<li><strong>\u00dcberdosis<\/strong>Eine Einzeldosis von 200 mg ist bei Erwachsenen selten t\u00f6dlich (hohe therapeutische Breite), Dosen \u00fcber 1 g bergen jedoch ein hohes Risiko. Naloxon hebt die Wirkung von Opioiden teilweise auf.<\/li>\n<li><strong>Schwangerschaft<\/strong>: Kategorie C; Meldung \u00fcber Entzugserscheinungen bei Neugeborenen (FDA REMS-Programm).<\/li>\n<\/ul>\n<h4>Pharmakokinetik<\/h4>\n<ul>\n<li><strong>Bioverf\u00fcgbarkeit<\/strong>: 75% (ER-Form)<\/li>\n<li><strong>Halbwertszeit<\/strong>: 6-7 Stunden (bei \u00e4lteren Menschen\/Niereninsuffizienz verl\u00e4ngert: bis zu 16 Stunden)<\/li>\n<li><strong>Stoffwechsel<\/strong>: CYP2D6 wird zu aktivem O-Desmethyltramadol umgewandelt (langsame Metabolisierer: 7-10 % der Bev\u00f6lkerung, reduzierte Wirksamkeit)<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\"><strong>Beweisquellen<\/strong>: FDA label (Ultram ER, 2006), EMA SmPC, BNF 2023, studies in\u00a0<em>Schmerz<\/em>\u00a0(z. B. DOI:10.1016\/j.pain.2006.08.005).<\/p>\n<p class=\"mb-2 last:mb-0\"><strong>Kritischer Hinweis<\/strong>Dies sind allgemeine Informationen, keine medizinische Beratung. Die Dosierung muss individuell von einem Arzt festgelegt werden \u2013 200 mg sind nicht f\u00fcr jeden geeignet (z. B. maximal 300 mg\/Tag bei \u00e4lteren Menschen). Selbstmedikation birgt das Risiko einer \u00dcberdosierung, Abh\u00e4ngigkeit oder des Todes. Konsultieren Sie bei Bedarf einen Arzt oder Apotheker und beachten Sie die geltenden Bestimmungen.<\/p>\n<\/div>\n\n    <div class=\"xs_social_share_widget xs_share_url after_content \t\tmain_content  wslu-style-1 wslu-share-box-shaped wslu-fill-colored wslu-none wslu-share-horizontal wslu-theme-font-no wslu-main_content\">\n\n\t\t\n        <ul>\n\t\t\t        <\/ul>\n    <\/div>","protected":false},"excerpt":{"rendered":"<p>Tramadol 200mg Tramadol 200mg is a synthetic opioid analgesic used to treat moderate to moderately severe pain. The 200mg dose is a higher-strength extended-release (ER) formulation, typically prescribed for around-the-clock pain management rather than as-needed use. Here&#8217;s a factual breakdown based on established medical sources like the FDA, EMA, and pharmacology references (e.g., Lexicomp, Micromedex): &hellip; <a href=\"https:\/\/trusthillpharmacy.de\/de\/shop\/tramadol-200-mg\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Tramadol 200 mg<\/span><\/a><\/p>","protected":false},"featured_media":8029,"template":"","meta":{"postBodyCss":"","postBodyMargin":[],"postBodyPadding":[],"postBodyBackground":{"backgroundType":"classic","gradient":""}},"product_brand":[],"product_cat":[15],"product_tag":[236],"class_list":{"0":"post-8018","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-uncategorized","7":"product_tag-tramadol-200mg","10":"instock","11":"shipping-taxable","12":"purchasable","13":"product-type-simple"},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.5 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Tramadol 200mg - 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Es bietet eine kontinuierliche, 24-Stunden-Linderung und reduziert die Notwendigkeit einer h\u00e4ufigen Dosierung.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/trusthillpharmacy.de\/de\/shop\/tramadol-200-mg\/","og_locale":"de_DE","og_type":"article","og_title":"Tramadol 200mg","og_description":"Tramadol 200mg is a synthetic opioid analgesic for moderate to provides continuous, around-the-clock relief and reduces the need for frequent dosing.","og_url":"https:\/\/trusthillpharmacy.de\/de\/shop\/tramadol-200-mg\/","og_site_name":"Trusthill Pharmacy","article_modified_time":"2026-04-24T00:16:16+00:00","og_image":[{"width":1000,"height":1000,"url":"https:\/\/trusthillpharmacy.de\/wp-content\/uploads\/2026\/04\/photo_5136777587941117594_y.jpg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","twitter_misc":{"Gesch\u00e4tzte Lesezeit":"3\u00a0Minuten"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/trusthillpharmacy.de\/shop\/tramadol-200mg\/","url":"https:\/\/trusthillpharmacy.de\/shop\/tramadol-200mg\/","name":"Tramadol 200 mg - Trusthill Apotheke","isPartOf":{"@id":"https:\/\/trusthillpharmacy.de\/#website"},"primaryImageOfPage":{"@id":"https:\/\/trusthillpharmacy.de\/shop\/tramadol-200mg\/#primaryimage"},"image":{"@id":"https:\/\/trusthillpharmacy.de\/shop\/tramadol-200mg\/#primaryimage"},"thumbnailUrl":"https:\/\/trusthillpharmacy.de\/wp-content\/uploads\/2026\/04\/photo_5136777587941117594_y.jpg","datePublished":"2026-04-22T22:20:32+00:00","dateModified":"2026-04-24T00:16:16+00:00","description":"Tramadol 200 mg ist ein synthetisches Opioid-Analgetikum zur Behandlung von m\u00e4\u00dfigen bis schweren Schmerzen. 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