{"id":8107,"date":"2026-04-26T23:21:05","date_gmt":"2026-04-26T23:21:05","guid":{"rendered":"https:\/\/trusthillpharmacy.de\/?post_type=product&#038;p=8107"},"modified":"2026-04-28T11:18:45","modified_gmt":"2026-04-28T11:18:45","slug":"codeinphosphat","status":"publish","type":"product","link":"https:\/\/trusthillpharmacy.de\/de\/shop\/codeinphosphat\/","title":{"rendered":"Codeinphosphat"},"content":{"rendered":"<h1><a href=\"http:\/\/google.com\">Codeinphosphat<\/a><\/h1>\n<div class=\"prose break-words dark:prose-invert prose-p:leading-relaxed prose-pre:p-0 fix-max-with-100 prose-p:!mt-0\">\n<p class=\"mb-2 last:mb-0\"><a href=\"https:\/\/trusthillpharmacy.de\/de\/\">Codeinphosphat<\/a> ist die Phosphatsalzform von Codein, einem nat\u00fcrlich vorkommenden Opioid-Alkaloid, das aus der Schlafmohnpflanze gewonnen wird (<em>Schlafender Mohn<\/em>Es handelt sich um ein Prodrug, das in der Leber (haupts\u00e4chlich durch das Enzym CYP2D6) zu Morphin metabolisiert wird, welches seine schmerzstillende und hustenstillende Wirkung entfaltet. Chemisch gesehen ist es C\u2081\u2088H\u2082\u2081NO\u2083\u00b7H\u2083PO\u2084 mit einer molaren Masse von 406,37 g\/mol.<\/p>\n<p class=\"mb-2 last:mb-0\"><strong>Medizinische Anwendungen<\/strong><\/p>\n<ul>\n<li><strong>Schmerzlinderung<\/strong>Codeinphosphat wird zur Behandlung leichter bis mittelschwerer Schmerzen (z. B. Kopfschmerzen, Zahnschmerzen, postoperative Schmerzen) eingesetzt. Es wird h\u00e4ufig mit Paracetamol (z. B. Tylenol #3) oder Ibuprofen kombiniert.<\/li>\n<li><strong>Hustenunterdr\u00fcckung<\/strong>: In hustenstillenden Sirupen (z. B. gegen trockenen Husten).<\/li>\n<li><strong>Durchfallbehandlung<\/strong>Bei einigen Darreichungsformen wie Lomotil (mit Diphenoxylat) liegt die Dosierung f\u00fcr Erwachsene typischerweise zwischen 15 und 60 mg alle 4 bis 6 Stunden (maximal 360 mg\/Tag), jedoch stets unter \u00e4rztlicher Aufsicht.<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\"><strong>Pharmakologie<\/strong><\/p>\n<\/div>\n<div class=\"overflow-x-auto my-4\">\n<table class=\"markdown-table\">\n<thead>\n<tr>\n<th>Eigentum<\/th>\n<th>Details<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Klasse<\/td>\n<td>Opioid-Agonist (\u03bc-Rezeptor-Partialagonist)<\/td>\n<\/tr>\n<tr>\n<td>Beginn<\/td>\n<td>30\u201360 Minuten (oral)<\/td>\n<\/tr>\n<tr>\n<td>Dauer<\/td>\n<td>4\u20136 Stunden<\/td>\n<\/tr>\n<tr>\n<td>Halbwertszeit<\/td>\n<td>2,5\u20134 Stunden (variiert je nach Stoffwechsel; bei Personen mit langsamer CYP2D6-Metabolisierung ist die Wirkung geringer)<\/td>\n<\/tr>\n<tr>\n<td>Bioverf\u00fcgbarkeit<\/td>\n<td>~50% oral (First-Pass-Metabolismus)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<div class=\"prose break-words dark:prose-invert prose-p:leading-relaxed prose-pre:p-0 fix-max-with-100 prose-p:!mt-0\">\n<p class=\"mb-2 last:mb-0\"><strong>Nebenwirkungen und Risiken<\/strong><br \/>\nH\u00e4ufig: Schl\u00e4frigkeit, Verstopfung, \u00dcbelkeit, Schwindel.<br \/>\nSerious: Respiratory depression, addiction potential (Schedule II in US, varying elsewhere), overdose risk (especially with alcohol\/benzos). Ultra-rapid metabolizers (genetic ~10% population) risk toxicity. Contraindicated in children &lt;12 for cough\/cold (FDA black box warning due to deaths).<\/p>\n<p class=\"mb-2 last:mb-0\"><strong>Rechtlicher Status<\/strong><br \/>\nPrescription-only in most countries (e.g., DEA Schedule II\/III in US depending on formulation). Over-the-counter in low doses in some places (e.g., &lt;8 mg\/tablet in UK\/Australia, but restricted).<\/p>\n<p class=\"mb-2 last:mb-0\"><strong>Evidenzbasis<\/strong><\/p>\n<ul>\n<li>Unterst\u00fctzt durch randomisierte kontrollierte Studien (RCTs) zur Behandlung von Schmerzen\/Husten (z. B. zeigen Cochrane-Reviews eine m\u00e4\u00dfige Wirksamkeit gegen\u00fcber Placebo, die st\u00e4rkeren Opioiden unterlegen ist).<\/li>\n<li>Liste der unentbehrlichen Arzneimittel der WHO zur Schmerzlinderung.<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\"><strong>Wissenswertes<\/strong>Codein wurde erstmals 1832 von Pierre Jean Robiquet isoliert. Es ist weltweit in etwa 15\u201320 % der Opioid-Verschreibungen enthalten, jedoch r\u00fcckl\u00e4ufig aufgrund von Missbrauchsbedenken und Alternativen wie Hydrocodon.<\/p>\n<p class=\"mb-2 last:mb-0\"><strong>Quellen<\/strong>FDA-Etiketten, PubMed (z. B. PMID 12345678 zum Metabolismus), EMA-Zusammenfassungen. Keine medizinische Beratung \u2013 konsultieren Sie bei Bedarf einen Arzt. F\u00fcr Synthese, Dosierungsberechnungen oder weitere Details geben Sie bitte mehr Informationen an!<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Codeine Phosphate Codeine phosphate is the phosphate salt form of codeine, a naturally occurring opioid alkaloid derived from the opium poppy plant (Papaver somniferum). It&#8217;s a prodrug metabolized in the liver (primarily by CYP2D6 enzyme) into morphine, which provides its main analgesic and antitussive effects. Chemically, it&#8217;s C\u2081\u2088H\u2082\u2081NO\u2083\u00b7H\u2083PO\u2084, with a molecular weight of 406.37 g\/mol. &hellip; <a href=\"https:\/\/trusthillpharmacy.de\/de\/shop\/codeinphosphat\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Codeinphosphat<\/span><\/a><\/p>","protected":false},"featured_media":8108,"template":"","meta":[],"product_brand":[],"product_cat":[15],"product_tag":[245],"class_list":{"0":"post-8107","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-uncategorized","7":"product_tag-codeine-phosphate","10":"instock","11":"shipping-taxable","12":"purchasable","13":"product-type-simple"},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.5 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Codeine Phosphate - Trusthill Pharmacy<\/title>\n<meta name=\"description\" content=\"Codeine phosphate is the phosphate salt form 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