{"id":8114,"date":"2026-04-26T23:37:09","date_gmt":"2026-04-26T23:37:09","guid":{"rendered":"https:\/\/trusthillpharmacy.de\/?post_type=product&#038;p=8114"},"modified":"2026-04-28T11:43:26","modified_gmt":"2026-04-28T11:43:26","slug":"demerol-100-mg","status":"publish","type":"product","link":"https:\/\/trusthillpharmacy.de\/de\/shop\/demerol-100-mg\/","title":{"rendered":"Demerol 100 mg"},"content":{"rendered":"<h1><a href=\"http:\/\/google.com\">Demerol 100 mg<\/a><\/h1>\n<div class=\"prose break-words dark:prose-invert prose-p:leading-relaxed prose-pre:p-0 fix-max-with-100 prose-p:!mt-0\">\n<p class=\"mb-2 last:mb-0\">\u00a0<a href=\"https:\/\/trusthillpharmacy.de\/de\/\">Demerol 100 mg<\/a> ist ein Markenname f\u00fcr <strong>Meperidinhydrochlorid<\/strong>Es handelt sich um ein synthetisches Opioid-Analgetikum (Schmerzmittel) aus der Gruppe der Phenylpiperidine. Die 100-mg-Dosis bezieht sich auf eine g\u00e4ngige Tabletten-, Injektions- oder Sirupst\u00e4rke zur Linderung m\u00e4\u00dfiger bis starker Schmerzen. In den USA unterliegt es aufgrund seines hohen Missbrauchspotenzials und der Suchtgefahr der Bet\u00e4ubungsmittelverordnung der Kategorie II.<\/p>\n<p class=\"mb-2 last:mb-0\"><strong>Hauptverwendungszwecke<\/strong>\u00a0(FDA-zugelassen):<\/p>\n<ul>\n<li>Kurzfristige Behandlung von m\u00e4\u00dfigen bis starken akuten Schmerzen (z. B. nach Operationen, Verletzungen).<\/li>\n<li>Manchmal wird es als Pr\u00e4medikation vor der Narkose oder zur Linderung von Wehenschmerzen eingesetzt (heutzutage jedoch seltener aufgrund sichererer Alternativen).<\/li>\n<li>Nicht empfohlen bei chronischen Schmerzen aufgrund von Risiken wie Toleranzentwicklung und Toxizit\u00e4t durch einen Metaboliten namens Normeperidin.<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\"><strong>So funktioniert es<\/strong>:<\/p>\n<ul>\n<li>Wirkt im zentralen Nervensystem als Mu-Opioid-Rezeptor-Agonist, blockiert Schmerzsignale und erzeugt Euphorie\/Sedierung.<\/li>\n<li>Wirkungseintritt: 15-30 Minuten (oral); maximale Wirkung: 1-2 Stunden; Wirkungsdauer: 2-4 Stunden.<\/li>\n<li>Halbwertszeit: ca. 2-5 Stunden (l\u00e4nger bei \u00e4lteren Menschen\/Niereninsuffizienz).<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\"><strong>Dosierung Leitlinien<\/strong>\u00a0(Erwachsene, gem\u00e4\u00df g\u00e4ngigen medizinischen Nachschlagewerken wie Lexicomp\/UpToDate):<\/p>\n<\/div>\n<div class=\"overflow-x-auto my-4\">\n<table class=\"markdown-table\">\n<thead>\n<tr>\n<th>Route<\/th>\n<th>\u00dcbliche Anfangsdosis<\/th>\n<th>Maximale Tagesdosis<\/th>\n<th>Notes<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Oral<\/td>\n<td>50-150 mg alle 3-4 Stunden<\/td>\n<td>600 mg<\/td>\n<td>Tabletten\/Sirup; Nahrung lindert \u00dcbelkeit.<\/td>\n<\/tr>\n<tr>\n<td>IM\/IV<\/td>\n<td>50-100 mg alle 3-4 Stunden<\/td>\n<td>400 mg (i.m.), 600 mg (i.v.)<\/td>\n<td>Injektionen zur schnellen Linderung; die intraven\u00f6se Gabe muss langsam erfolgen, um eine Atemdepression zu vermeiden.<\/td>\n<\/tr>\n<tr>\n<td>\u00c4ltere Menschen\/Nieren<\/td>\n<td>Um 25-50 % reduzieren<\/td>\n<td>Untere Grenzwerte<\/td>\n<td>Eine Anreicherung von Normeperidin birgt das Risiko von Krampfanf\u00e4llen.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<div class=\"prose break-words dark:prose-invert prose-p:leading-relaxed prose-pre:p-0 fix-max-with-100 prose-p:!mt-0\">\n<p class=\"mb-2 last:mb-0\"><em>Befolgen Sie stets die Anweisungen des Arztes; nehmen Sie keine Selbstkorrekturen vor.<\/em><\/p>\n<p class=\"mb-2 last:mb-0\"><strong>H\u00e4ufige Nebenwirkungen<\/strong>:<\/p>\n<ul>\n<li>Leichte Nebenwirkungen: Schl\u00e4frigkeit, Schwindel, \u00dcbelkeit, Verstopfung, Schwitzen.<\/li>\n<li>Schwerwiegend: Atemdepression, niedriger Blutdruck, Krampfanf\u00e4lle (durch Normeperidin, insbesondere bei einer Anwendungsdauer von &gt;48 Stunden), Serotonin-Syndrom (bei gleichzeitiger Anwendung mit SSRIs\/MAOIs).<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\"><strong>Warnhinweise und Risiken<\/strong>\u00a0(Black Box der FDA):<\/p>\n<ul>\n<li><strong>\u00dcberdosis<\/strong>Kann zu Koma und Atemstillstand f\u00fchren \u2013 Naloxon hebt dies auf.<\/li>\n<li><strong>Abh\u00e4ngigkeit\/ - Entzug<\/strong>Hohes Risiko; nach l\u00e4ngerer Anwendung ein abruptes Absetzen vermeiden.<\/li>\n<li><strong>Kontraindikationen<\/strong>: Nicht anwenden bei gleichzeitiger Einnahme von MAO-Hemmern (innerhalb von 14 Tagen), bei schweren Atemwegserkrankungen, akutem Asthma oder paralytischem Ileus.<\/li>\n<li><strong>Arzneimittelwechselwirkungen<\/strong>: Verst\u00e4rkt die Wirkung von ZNS-d\u00e4mpfenden Mitteln (Alkohol, Benzodiazepine, andere Opioide); Risiko einer QT-Verl\u00e4ngerung.<\/li>\n<li><strong>Schwangerschaft<\/strong>Kategorie C; nur anwenden, wenn der Nutzen die Risiken \u00fcberwiegt (Absetzen bei Neugeborenen m\u00f6glich).<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\"><strong>Beweise &amp; Fakten<\/strong>:<\/p>\n<ul>\n<li>Wirksamkeit: Laut Cochrane-Reviews wirksam bei akuten Schmerzen, jedoch Morphin bei starken Schmerzen unterlegen und langfristig riskanter (Normeperidin-Toxizit\u00e4t wurde in Studien wie z. B. dokumentiert).\u00a0<em>NEJM<\/em>\u00a0F\u00e4lle aus den 1980er Jahren).<\/li>\n<li>R\u00fcckgang der Anwendung: Die CDC-Richtlinien (2022) bevorzugen Nicht-Opioide; der Meperidin-Gebrauch ist in Krankenh\u00e4usern seit den 2000er Jahren aufgrund sichererer Alternativen wie Morphin\/Hydromorphon um 90 % zur\u00fcckgegangen.<\/li>\n<li>Stra\u00dfenwert\/Missbrauch: ~1-5 US-Dollar pro 100-mg-Pille (DEA-Daten); wird oft wegen Euphorie missbraucht.<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\"><strong>Dies ist kein medizinischer Rat.<\/strong>\u2014Bei Fragen zur Anwendung vorab einen Arzt oder Apotheker konsultieren. Bei Anzeichen einer \u00dcberdosierung (langsame Atmung, Bewusstlosigkeit) sofort den Notruf w\u00e4hlen.<\/p>\n<\/div>\n\n    <div class=\"xs_social_share_widget xs_share_url after_content \t\tmain_content  wslu-style-1 wslu-share-box-shaped wslu-fill-colored wslu-none wslu-share-horizontal wslu-theme-font-no wslu-main_content\">\n\n\t\t\n        <ul>\n\t\t\t        <\/ul>\n    <\/div>","protected":false},"excerpt":{"rendered":"<p>Demerol 100mg \u00a0Demerol 100mg is a brand name for meperidine hydrochloride, a synthetic opioid analgesic (painkiller) from the phenylpiperidine class. The 100 mg dose refers to a common tablet, injection, or syrup strength used for moderate to severe pain relief. It&#8217;s a Schedule II controlled substance in the US due to high abuse potential and &hellip; <a href=\"https:\/\/trusthillpharmacy.de\/de\/shop\/demerol-100-mg\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Demerol 100 mg<\/span><\/a><\/p>","protected":false},"featured_media":8119,"comment_status":"closed","ping_status":"closed","template":"","meta":{"postBodyCss":"","postBodyMargin":[],"postBodyPadding":[],"postBodyBackground":{"backgroundType":"classic","gradient":""}},"product_brand":[],"product_cat":[15],"product_tag":[247],"class_list":["post-8114","product","type-product","status-publish","has-post-thumbnail","product_cat-uncategorized","product_tag-demerol-100mg","instock","shipping-taxable","purchasable","product-type-simple"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.5 (Yoast SEO v28.1) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Demerol 100mg - Trusthill 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