{"id":8217,"date":"2026-05-08T19:36:33","date_gmt":"2026-05-08T19:36:33","guid":{"rendered":"https:\/\/trusthillpharmacy.de\/?post_type=product&#038;p=8217"},"modified":"2026-05-09T16:22:27","modified_gmt":"2026-05-09T16:22:27","slug":"codeinphosphat-2","status":"publish","type":"product","link":"https:\/\/trusthillpharmacy.de\/de\/shop\/codeinphosphat-2\/","title":{"rendered":"Codeinphosphat"},"content":{"rendered":"<h1><a href=\"http:\/\/google.com\">Codeinphosphat<\/a><\/h1>\n<div class=\"prose break-words dark:prose-invert prose-p:leading-relaxed prose-pre:p-0 fix-max-with-100 prose-p:!mt-0\">\n<p class=\"mb-2 last:mb-0\"><a href=\"https:\/\/trusthillpharmacy.de\/de\/\">Codeinphosphat<\/a> ist die Phosphatsalzform von Codein, einem nat\u00fcrlich vorkommenden Opioid-Alkaloid, das aus dem Schlafmohn gewonnen wird (<em>Schlafender Mohn<\/em>Es handelt sich um ein Prodrug, das in der Leber (haupts\u00e4chlich durch das Enzym CYP2D6) zu Morphin metabolisiert wird, welches seine schmerzlindernde Wirkung entfaltet. Chemisch gesehen ist es C\u2081\u2088H\u2082\u2081NO\u2083\u00b7H\u2083PO\u2084 mit einer molaren Masse von 406,37 g\/mol.<\/p>\n<p class=\"mb-2 last:mb-0\"><strong>Medizinische Anwendungen<\/strong><\/p>\n<ul>\n<li><strong>Schmerzlinderung<\/strong>Leichte bis mittelschwere Schmerzen (z. B. nach Operationen oder Zahnbehandlungen). Oft in Kombination mit Paracetamol (z. B. Tylenol #3) oder Ibuprofen.<\/li>\n<li><strong>Hustenunterdr\u00fcckung<\/strong>: Antitussivum in Sirupen (z. B. bei trockenem Husten).<\/li>\n<li><strong>Mittel gegen Durchfall<\/strong>: In niedrigen Dosen (z.B. als Bestandteil von Lomotil mit Diphenoxylat).<br \/>\nDie \u00fcbliche Dosierung liegt bei Erwachsenen zwischen 15 und 60 mg alle 4 bis 6 Stunden (maximal 360 mg\/Tag), jedoch kann es bei ultraschnellen CYP2D6-Metabolisierern bereits bei Standarddosen zu Toxizit\u00e4t kommen.<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\"><strong>Pharmakologie<\/strong><\/p>\n<\/div>\n<div class=\"overflow-x-auto my-4\">\n<table class=\"markdown-table\">\n<thead>\n<tr>\n<th>Eigentum<\/th>\n<th>Details<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Klasse<\/td>\n<td>Opioid-Agonist (\u03bc-Rezeptor-Partialagonist)<\/td>\n<\/tr>\n<tr>\n<td>Beginn<\/td>\n<td>30\u201360 Minuten (oral); maximale Wirkung nach 1\u20132 Stunden<\/td>\n<\/tr>\n<tr>\n<td>Dauer<\/td>\n<td>4\u20136 Stunden<\/td>\n<\/tr>\n<tr>\n<td>Halbwertszeit<\/td>\n<td>2,5\u20134 Stunden (Codein); 2\u20134 Stunden (Morphinmetabolit)<\/td>\n<\/tr>\n<tr>\n<td>Bioverf\u00fcgbarkeit<\/td>\n<td>~50% oral (First-Pass-Metabolismus)<\/td>\n<\/tr>\n<tr>\n<td>Ausscheidung<\/td>\n<td>Urin (10 % unver\u00e4ndert; Rest als Metaboliten)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<div class=\"prose break-words dark:prose-invert prose-p:leading-relaxed prose-pre:p-0 fix-max-with-100 prose-p:!mt-0\">\n<p class=\"mb-2 last:mb-0\"><strong>Nebenwirkungen und Risiken<\/strong><\/p>\n<ul>\n<li><strong>Common<\/strong>Schl\u00e4frigkeit, Verstopfung, \u00dcbelkeit, Schwindel, Juckreiz.<\/li>\n<li><strong>Ernst<\/strong>: Atemdepression (dosisabh\u00e4ngig; h\u00f6chstes Risiko bei &gt;200 mg\/Tag), Sucht\/Abh\u00e4ngigkeit, \u00dcberdosierung (stecknadelkopfgro\u00dfe Pupillen, Koma).<\/li>\n<li><strong>Kontraindikationen<\/strong>: Respiratory depression, acute asthma, paralytic ileus, children &lt;12 (FDA black box for cough\/cold due to apnea risk), breastfeeding (morphine in milk).<\/li>\n<li><strong>Wechselwirkungen<\/strong>CYP2D6-Inhibitoren (z. B. Fluoxetin) verringern die Wirksamkeit; Beruhigungsmittel\/Alkohol verst\u00e4rken die Depression.<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\"><strong>Rechtlicher Status<\/strong><br \/>\nIn den USA unterliegt diese Substanz der Kategorie II der Bet\u00e4ubungsmittelkontrolle (hohes Missbrauchspotenzial); weltweit verschreibungspflichtig. \u00dcberdosierung wird mit Naloxon behandelt.<\/p>\n<p class=\"mb-2 last:mb-0\"><strong>Evidenzbasis<\/strong><\/p>\n<ul>\n<li>WHO-Liste der unentbehrlichen Arzneimittel (Analgetika).<\/li>\n<li>Studien (z. B. Cochrane Reviews) zeigen eine m\u00e4\u00dfige Wirksamkeit bei Schmerzen\/Husten im Vergleich zu Placebo, die st\u00e4rkeren Opioiden wie Morphin unterlegen ist.<\/li>\n<li>Gentests werden f\u00fcr Personen mit langsamem\/ultraschnellem Metabolismus empfohlen (z. B. sind ca. 10 % der Kaukasier langsam; 1\u20132 % ultraschnell).<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\"><strong>Wissenswertes<\/strong>Codein wurde erstmals 1832 von Pierre Jean Robiquet isoliert. Der Freizeitkonsum erfolgt h\u00e4ufig durch Extraktion aus rezeptfreien Kombinationspillen (z. B. \u201eLean\u201c mit Promethazin), wobei die Reinheit stark variiert.<\/p>\n<h3>Warnungen:<\/h3>\n<ul>\n<li><strong>Illegale Quellen<\/strong>Der Handel mit Drogen im Darknet, auf der Stra\u00dfe oder \u00fcber unregulierte ausl\u00e4ndische Seiten (z. B. aus Indien\/Mexiko) birgt das Risiko von F\u00e4lschungen, Fentanyl-Verunreinigung, Verhaftung oder Tod. In den USA drohen bei Drogenhandel bis zu 20 Jahre Haft oder hohe Geldstrafen.<\/li>\n<li><strong>Globale Trends<\/strong>: Interpol\/FDA seize millions in illicit shipments yearly; purity often &lt;50%.<\/li>\n<li><strong>Sicherere Alternativen<\/strong>Bei Schmerzen \u2013 Ibuprofen\/Paracetamol; bei Husten \u2013 Dextromethorphan (rezeptfrei erh\u00e4ltlich).<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\"><strong>Dies ist keine medizinische\/rechtliche Beratung \u2013 bitte informieren Sie sich \u00fcber die geltenden Gesetze (z. B. DEA.gov, EMA.europa.eu).<\/strong>\u00a0Wenn Sie es aus gesundheitlichen Gr\u00fcnden ben\u00f6tigen, sprechen Sie mit einem Arzt.<\/p>\n<\/div>\n\n    <div class=\"xs_social_share_widget xs_share_url after_content \t\tmain_content  wslu-style-1 wslu-share-box-shaped wslu-fill-colored wslu-none wslu-share-horizontal wslu-theme-font-no wslu-main_content\">\n\n\t\t\n        <ul>\n\t\t\t        <\/ul>\n    <\/div>","protected":false},"excerpt":{"rendered":"<p>Codeine Phosphate Codeine phosphate is the phosphate salt form of codeine, a naturally occurring opioid alkaloid derived from the opium poppy (Papaver somniferum). It&#8217;s a prodrug metabolized in the liver (primarily by CYP2D6 enzyme) into morphine, which provides its main analgesic effects. Chemically, it&#8217;s C\u2081\u2088H\u2082\u2081NO\u2083\u00b7H\u2083PO\u2084, with a molecular weight of 406.37 g\/mol. Medical Uses Pain &hellip; <a href=\"https:\/\/trusthillpharmacy.de\/de\/shop\/codeinphosphat-2\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Codeinphosphat<\/span><\/a><\/p>","protected":false},"featured_media":8231,"comment_status":"closed","ping_status":"closed","template":"","meta":{"postBodyCss":"","postBodyMargin":[],"postBodyPadding":[],"postBodyBackground":{"backgroundType":"classic","gradient":""}},"product_brand":[],"product_cat":[15],"product_tag":[245],"class_list":["post-8217","product","type-product","status-publish","has-post-thumbnail","product_cat-uncategorized","product_tag-codeine-phosphate","instock","shipping-taxable","purchasable","product-type-variable"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.5 (Yoast SEO v28.1) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Codeine Phosphate - Trusthill Pharmacy<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/trusthillpharmacy.de\/de\/shop\/codeinphosphat-2\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Codeine Phosphate\" \/>\n<meta property=\"og:description\" content=\"Codeine Phosphate Codeine phosphate is the phosphate salt form of codeine, a naturally occurring opioid alkaloid derived from the opium poppy (Papaver somniferum). It&#8217;s a prodrug metabolized in the liver (primarily by CYP2D6 enzyme) into morphine, which provides its main analgesic effects. Chemically, it&#8217;s C\u2081\u2088H\u2082\u2081NO\u2083\u00b7H\u2083PO\u2084, with a molecular weight of 406.37 g\/mol. 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It&#8217;s a prodrug metabolized in the liver (primarily by CYP2D6 enzyme) into morphine, which provides its main analgesic effects. Chemically, it&#8217;s C\u2081\u2088H\u2082\u2081NO\u2083\u00b7H\u2083PO\u2084, with a molecular weight of 406.37 g\/mol. 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