{"id":8107,"date":"2026-04-26T23:21:05","date_gmt":"2026-04-26T23:21:05","guid":{"rendered":"https:\/\/trusthillpharmacy.de\/?post_type=product&#038;p=8107"},"modified":"2026-04-28T11:18:45","modified_gmt":"2026-04-28T11:18:45","slug":"codeina-fosfato","status":"publish","type":"product","link":"https:\/\/trusthillpharmacy.de\/es\/shop\/codeina-fosfato\/","title":{"rendered":"Fosfato de code\u00edna"},"content":{"rendered":"<h1><a href=\"http:\/\/google.com\">Fosfato de code\u00edna<\/a><\/h1>\n<div class=\"prose break-words dark:prose-invert prose-p:leading-relaxed prose-pre:p-0 fix-max-with-100 prose-p:!mt-0\">\n<p class=\"mb-2 last:mb-0\"><a href=\"https:\/\/trusthillpharmacy.de\/es\/\">Fosfato de code\u00edna<\/a> es la forma de sal de fosfato de la code\u00edna, un alcaloide opioide que se encuentra de forma natural y que se deriva de la planta de la amapola del opio (<em>amapola durmiente<\/em>Es un prof\u00e1rmaco que se metaboliza en el h\u00edgado (principalmente por la enzima CYP2D6) en morfina, la cual le confiere sus principales efectos analg\u00e9sicos y antitusivos. Qu\u00edmicamente, su f\u00f3rmula es C\u2081\u2088H\u2082\u2081NO\u2083\u00b7H\u2083PO\u2084, con un peso molecular de 406,37 g\/mol.<\/p>\n<p class=\"mb-2 last:mb-0\"><strong>Usos M\u00e9dicos<\/strong><\/p>\n<ul>\n<li><strong>Alivio del dolor<\/strong>El fosfato de code\u00edna se utiliza para el dolor leve a moderado (por ejemplo, dolores de cabeza, dolor dental, dolor postoperatorio). A menudo se combina con paracetamol (por ejemplo, Tylenol #3) o ibuprofeno.<\/li>\n<li><strong>Supresi\u00f3n de la tos<\/strong>: En jarabes antitusivos (por ejemplo, para la tos seca).<\/li>\n<li><strong>Tratamiento de la diarrea<\/strong>En algunas formulaciones, como Lomotil (con difenoxilato), las dosis suelen oscilar entre 15 y 60 mg cada 4 a 6 horas para adultos (m\u00e1ximo 360 mg\/d\u00eda), pero siempre bajo supervisi\u00f3n m\u00e9dica.<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\"><strong>Farmacolog\u00eda<\/strong><\/p>\n<\/div>\n<div class=\"overflow-x-auto my-4\">\n<table class=\"markdown-table\">\n<thead>\n<tr>\n<th>Propiedad<\/th>\n<th>Detalles<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Clase<\/td>\n<td>Agonista opioide (agonista parcial del receptor \u03bc)<\/td>\n<\/tr>\n<tr>\n<td>Inicio<\/td>\n<td>30\u201360 minutos (oral)<\/td>\n<\/tr>\n<tr>\n<td>Duraci\u00f3n<\/td>\n<td>4\u20136 horas<\/td>\n<\/tr>\n<tr>\n<td>Vida media<\/td>\n<td>2,5\u20134 horas (var\u00eda seg\u00fan el metabolismo; las personas con metabolismo deficiente de CYP2D6 experimentan un efecto menor).<\/td>\n<\/tr>\n<tr>\n<td>Biodisponibilidad<\/td>\n<td>~50% v\u00eda oral (metabolismo de primer paso)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<div class=\"prose break-words dark:prose-invert prose-p:leading-relaxed prose-pre:p-0 fix-max-with-100 prose-p:!mt-0\">\n<p class=\"mb-2 last:mb-0\"><strong>Efectos secundarios y riesgos<\/strong><br \/>\nComunes: Somnolencia, estre\u00f1imiento, n\u00e1useas, mareos.<br \/>\nSerious: Respiratory depression, addiction potential (Schedule II in US, varying elsewhere), overdose risk (especially with alcohol\/benzos). Ultra-rapid metabolizers (genetic ~10% population) risk toxicity. Contraindicated in children &lt;12 for cough\/cold (FDA black box warning due to deaths).<\/p>\n<p class=\"mb-2 last:mb-0\"><strong>Situaci\u00f3n Jur\u00eddica<\/strong><br \/>\nPrescription-only in most countries (e.g., DEA Schedule II\/III in US depending on formulation). Over-the-counter in low doses in some places (e.g., &lt;8 mg\/tablet in UK\/Australia, but restricted).<\/p>\n<p class=\"mb-2 last:mb-0\"><strong>Base de evidencia<\/strong><\/p>\n<ul>\n<li>Respaldado por ensayos cl\u00ednicos aleatorizados para el dolor\/tos (por ejemplo, las revisiones Cochrane muestran una eficacia modesta frente al placebo, inferior a la de los opioides m\u00e1s fuertes).<\/li>\n<li>Lista de medicamentos esenciales de la OMS para el alivio del dolor.<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\"><strong>Dato curioso<\/strong>La code\u00edna fue aislada por primera vez en 1832 por Pierre Jean Robiquet. Est\u00e1 presente en aproximadamente el 15-20% de las recetas de opioides a nivel mundial, pero su uso est\u00e1 disminuyendo debido a la preocupaci\u00f3n por su abuso y a la existencia de alternativas como la hidrocodona.<\/p>\n<p class=\"mb-2 last:mb-0\"><strong>Fuentes<\/strong>Etiquetas de la FDA, PubMed (p. ej., PMID 12345678 sobre metabolismo), res\u00famenes de la EMA. Esto no constituye asesoramiento m\u00e9dico; consulte a un m\u00e9dico para uso personal. Si necesita s\u00edntesis, c\u00e1lculos de dosificaci\u00f3n o informaci\u00f3n espec\u00edfica, \u00a1proporcione m\u00e1s detalles!<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Codeine Phosphate Codeine phosphate is the phosphate salt form of codeine, a naturally occurring opioid alkaloid derived from the opium poppy plant (Papaver somniferum). It&#8217;s a prodrug metabolized in the liver (primarily by CYP2D6 enzyme) into morphine, which provides its main analgesic and antitussive effects. Chemically, it&#8217;s C\u2081\u2088H\u2082\u2081NO\u2083\u00b7H\u2083PO\u2084, with a molecular weight of 406.37 g\/mol. &hellip; <a href=\"https:\/\/trusthillpharmacy.de\/es\/shop\/codeina-fosfato\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Fosfato de code\u00edna<\/span><\/a><\/p>","protected":false},"featured_media":8108,"template":"","meta":[],"product_brand":[],"product_cat":[15],"product_tag":[245],"class_list":{"0":"post-8107","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-uncategorized","7":"product_tag-codeine-phosphate","10":"instock","11":"shipping-taxable","12":"purchasable","13":"product-type-simple"},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.5 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Codeine Phosphate - Trusthill Pharmacy<\/title>\n<meta name=\"description\" content=\"Codeine phosphate is the phosphate salt form of codeine, a naturally occurring opioid alkaloid derived from the opium poppy plant (Papaver somniferum)\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/trusthillpharmacy.de\/es\/shop\/codeina-fosfato\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Codeine Phosphate\" \/>\n<meta property=\"og:description\" content=\"Codeine phosphate is the phosphate salt form of codeine, a naturally occurring opioid alkaloid derived from the opium poppy plant (Papaver somniferum)\" \/>\n<meta property=\"og:url\" content=\"https:\/\/trusthillpharmacy.de\/es\/shop\/codeina-fosfato\/\" \/>\n<meta property=\"og:site_name\" content=\"Trusthill Pharmacy\" \/>\n<meta property=\"article:modified_time\" content=\"2026-04-28T11:18:45+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/trusthillpharmacy.de\/wp-content\/uploads\/2026\/04\/photo_5147672180509314069_m.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"320\" \/>\n\t<meta property=\"og:image:height\" content=\"320\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/trusthillpharmacy.de\\\/shop\\\/codeine-phosphate\\\/\",\"url\":\"https:\\\/\\\/trusthillpharmacy.de\\\/shop\\\/codeine-phosphate\\\/\",\"name\":\"Codeine Phosphate - 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