{"id":8114,"date":"2026-04-26T23:37:09","date_gmt":"2026-04-26T23:37:09","guid":{"rendered":"https:\/\/trusthillpharmacy.de\/?post_type=product&#038;p=8114"},"modified":"2026-04-28T11:43:26","modified_gmt":"2026-04-28T11:43:26","slug":"demerol-100mg","status":"publish","type":"product","link":"https:\/\/trusthillpharmacy.de\/nl\/shop\/demerol-100mg\/","title":{"rendered":"Demerol 100 mg"},"content":{"rendered":"<h1><a href=\"http:\/\/google.com\">Demerol 100 mg<\/a><\/h1>\n<div class=\"prose break-words dark:prose-invert prose-p:leading-relaxed prose-pre:p-0 fix-max-with-100 prose-p:!mt-0\">\n<p class=\"mb-2 last:mb-0\">\u00a0<a href=\"https:\/\/trusthillpharmacy.de\/nl\/\">Demerol 100 mg<\/a> is een merknaam voor <strong>meperidinehydrochloride<\/strong>100 mg is een synthetisch opio\u00efde analgeticum (pijnstiller) uit de fenylpiperidineklasse. De dosis van 100 mg verwijst naar een gangbare sterkte voor tabletten, injecties of siroop, gebruikt voor de verlichting van matige tot ernstige pijn. Het is een gereguleerde stof van categorie II in de VS vanwege het hoge risico op misbruik en verslaving.<\/p>\n<p class=\"mb-2 last:mb-0\"><strong>Primaire toepassingen<\/strong>\u00a0(Goedgekeurd door de FDA):<\/p>\n<ul>\n<li>Kortetermijnbehandeling van matige tot ernstige acute pijn (bijv. na een operatie of letsel).<\/li>\n<li>Soms als premedicatie voor anesthesie of tegen wee\u00ebn (hoewel dit tegenwoordig minder vaak voorkomt vanwege veiligere alternatieven).<\/li>\n<li>Niet aanbevolen bij chronische pijn vanwege risico's zoals tolerantieopbouw en toxiciteit door een metaboliet genaamd normeperidine.<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\"><strong>Hoe het werkt<\/strong>:<\/p>\n<ul>\n<li>Het werkt als een mu-opio\u00efde receptoragonist in het centrale zenuwstelsel, blokkeert pijnsignalen en veroorzaakt euforie\/sedatie.<\/li>\n<li>Werking begint na 15-30 minuten (oraal); maximale werking na 1-2 uur; werkingsduur: 2-4 uur.<\/li>\n<li>Halfwaardetijd: ~2-5 uur (langer bij ouderen\/pati\u00ebnten met nierfunctiestoornis).<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\"><strong>Dosering Richtlijnen<\/strong>\u00a0(Volwassenen, volgens standaard medische naslagwerken zoals Lexicomp\/UpToDate):<\/p>\n<\/div>\n<div class=\"overflow-x-auto my-4\">\n<table class=\"markdown-table\">\n<thead>\n<tr>\n<th>Route<\/th>\n<th>Gebruikelijke startdosering<\/th>\n<th>Maximale dagelijkse dosis<\/th>\n<th>Opmerkingen<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Oraal<\/td>\n<td>50-150 mg elke 3-4 uur<\/td>\n<td>600 mg<\/td>\n<td>Tabletten\/siroop; voedsel vermindert misselijkheid.<\/td>\n<\/tr>\n<tr>\n<td>IM\/IV<\/td>\n<td>50-100 mg elke 3-4 uur<\/td>\n<td>400 mg (IM), 600 mg (IV)<\/td>\n<td>Injecties voor snelle verlichting; intraveneuze toediening moet langzaam verlopen om ademhalingsdepressie te voorkomen.<\/td>\n<\/tr>\n<tr>\n<td>Ouderen\/Nierpati\u00ebnten<\/td>\n<td>Verminder met 25-50%<\/td>\n<td>Ondergrenzen<\/td>\n<td>Een ophoping van normeperidine kan epileptische aanvallen veroorzaken.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<div class=\"prose break-words dark:prose-invert prose-p:leading-relaxed prose-pre:p-0 fix-max-with-100 prose-p:!mt-0\">\n<p class=\"mb-2 last:mb-0\"><em>Volg altijd de instructies van de arts; pas de medicatie niet zelf aan.<\/em><\/p>\n<p class=\"mb-2 last:mb-0\"><strong>Vaak Voorkomende Bijwerkingen<\/strong>:<\/p>\n<ul>\n<li>Milde bijwerkingen: Slaperigheid, duizeligheid, misselijkheid, constipatie, zweten.<\/li>\n<li>Ernstige bijwerkingen: Ademhalingsdepressie, lage bloeddruk, convulsies (door normeperidine, met name bij gebruik langer dan 48 uur), serotoninesyndroom (in combinatie met SSRI's\/MAO-remmers).<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\"><strong>Waarschuwingen en risico's<\/strong>\u00a0(Zwart kader van de FDA):<\/p>\n<ul>\n<li><strong>Overdosis<\/strong>Kan coma en ademhalingsstilstand veroorzaken; naloxon kan dit omkeren.<\/li>\n<li><strong>Verslaving\/Intrekking<\/strong>Hoog risico; vermijd abrupt stoppen na langdurig gebruik.<\/li>\n<li><strong>Contra-indicaties<\/strong>Vermijd gebruik in combinatie met MAO-remmers (binnen 14 dagen), bij ernstige ademhalingsproblemen, acute astma en paralytische ileus.<\/li>\n<li><strong>Geneesmiddelinteracties<\/strong>: Versterkt de werking van centraal zenuwstelselonderdrukkende middelen (alcohol, benzodiazepinen, andere opio\u00efden); risico op QT-verlenging.<\/li>\n<li><strong>Zwangerschap<\/strong>Categorie C; alleen gebruiken als de voordelen opwegen tegen de risico's (ontwenningsverschijnselen bij pasgeborenen mogelijk).<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\"><strong>Bewijs &amp; Feiten<\/strong>:<\/p>\n<ul>\n<li>Werkzaamheid: Effectief bij acute pijn volgens Cochrane-reviews, maar minder effectief dan morfine bij ernstige pijn en riskanter op de lange termijn (normeperidine-toxiciteit gedocumenteerd in studies zoals\u00a0<em>NEJM<\/em>\u00a0gevallen uit de jaren 1980).<\/li>\n<li>Afname in gebruik: Volgens de richtlijnen van de CDC (2022) wordt de voorkeur gegeven aan niet-opio\u00efden; het gebruik van meperidine is in ziekenhuizen sinds de jaren 2000 met 90% gedaald als gevolg van veiligere alternatieven zoals morfine\/hydromorfon.<\/li>\n<li>Straatwaarde\/misbruik: ~$1-5 per pil van 100 mg (DEA-gegevens); wordt vaak misbruikt voor euforie.<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\"><strong>Dit is geen medisch advies.<\/strong>\u2014Raadpleeg een arts\/apotheker voor persoonlijk gebruik. Bel bij een overdosis (trage ademhaling, bewusteloosheid) onmiddellijk de hulpdiensten.<\/p>\n<\/div>\n\n    <div class=\"xs_social_share_widget xs_share_url after_content \t\tmain_content  wslu-style-1 wslu-share-box-shaped wslu-fill-colored wslu-none wslu-share-horizontal wslu-theme-font-no wslu-main_content\">\n\n\t\t\n        <ul>\n\t\t\t        <\/ul>\n    <\/div>","protected":false},"excerpt":{"rendered":"<p>Demerol 100mg \u00a0Demerol 100mg is a brand name for meperidine hydrochloride, a synthetic opioid analgesic (painkiller) from the phenylpiperidine class. The 100 mg dose refers to a common tablet, injection, or syrup strength used for moderate to severe pain relief. It&#8217;s a Schedule II controlled substance in the US due to high abuse potential and &hellip; <a href=\"https:\/\/trusthillpharmacy.de\/nl\/shop\/demerol-100mg\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Demerol 100 mg<\/span><\/a><\/p>","protected":false},"featured_media":8119,"template":"","meta":{"postBodyCss":"","postBodyMargin":[],"postBodyPadding":[],"postBodyBackground":{"backgroundType":"classic","gradient":""}},"product_brand":[],"product_cat":[15],"product_tag":[247],"class_list":{"0":"post-8114","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-uncategorized","7":"product_tag-demerol-100mg","10":"instock","11":"shipping-taxable","12":"purchasable","13":"product-type-simple"},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.5 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Demerol 100mg - Trusthill Pharmacy<\/title>\n<meta name=\"description\" content=\"\u00a0Demerol 100mg is a brand name for meperidine hydrochloride, a synthetic opioid analgesic (painkiller) from the phenylpiperidine class.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/trusthillpharmacy.de\/nl\/shop\/demerol-100mg\/\" \/>\n<meta property=\"og:locale\" content=\"nl_NL\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Demerol 100mg\" \/>\n<meta property=\"og:description\" content=\"\u00a0Demerol 100mg is a brand name for meperidine hydrochloride, a synthetic opioid analgesic (painkiller) from the phenylpiperidine class.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/trusthillpharmacy.de\/nl\/shop\/demerol-100mg\/\" \/>\n<meta property=\"og:site_name\" content=\"Trusthill Pharmacy\" \/>\n<meta property=\"article:modified_time\" content=\"2026-04-28T11:43:26+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/trusthillpharmacy.de\/wp-content\/uploads\/2026\/04\/photo_5147672180509314073_x.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"450\" \/>\n\t<meta property=\"og:image:height\" content=\"450\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Geschatte leestijd\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minuten\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/trusthillpharmacy.de\\\/shop\\\/demerol-100mg\\\/\",\"url\":\"https:\\\/\\\/trusthillpharmacy.de\\\/shop\\\/demerol-100mg\\\/\",\"name\":\"Demerol 100mg - 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