{"id":8515,"date":"2026-05-17T00:58:24","date_gmt":"2026-05-17T00:58:24","guid":{"rendered":"https:\/\/trusthillpharmacy.de\/?post_type=product&#038;p=8515"},"modified":"2026-05-25T20:48:13","modified_gmt":"2026-05-25T20:48:13","slug":"3-cmc-capsules-220mg","status":"publish","type":"product","link":"https:\/\/trusthillpharmacy.de\/nl\/shop\/3-cmc-capsules-220mg\/","title":{"rendered":"3-CMC Capsules 220mg"},"content":{"rendered":"<h1><a href=\"http:\/\/google.com\">3-CMC Capsules<\/a> 220mg<\/h1>\n<p dir=\"auto\"><a href=\"https:\/\/trusthillpharmacy.de\/nl\/\">3-CMC Capsules<\/a> 220mg (also known as clophedrone) is a synthetic cathinone and novel psychoactive substance (NPS) belonging to the substituted cathinone class. It is <strong>not approved for any medical use<\/strong> and is sold primarily as a research chemical. A <strong>220mg capsule<\/strong> is considered a <strong>very high \/ heavy dose<\/strong> according to anecdotal reports and available data. Typical reported oral doses range from 20\u2013250mg, with many users describing strong effects above 150\u2013200mg.<\/p>\n<h3 dir=\"auto\">Farmacologie<\/h3>\n<p dir=\"auto\">3-CMC acts as a <strong>monoamine transporter substrate and releaser<\/strong>. It inhibits the reuptake and promotes the release of dopamine (DA), norepinephrine (NE), and serotonin (5-HT). It has a balanced but potent stimulant profile similar to other chlorinated cathinones like 4-CMC.<\/p>\n<ul dir=\"auto\">\n<li><strong>Aanvang (oraal)<\/strong>: 15\u201360 minutes<\/li>\n<li><strong>Piek<\/strong>: 1-3 uur<\/li>\n<li><strong>Duur<\/strong>: 3\u20136 hours (with after-effects lasting longer)<\/li>\n<\/ul>\n<p dir=\"auto\">It produces stimulant and empathogenic effects, including euphoria, increased energy, sociability, and elevated heart rate\/blood pressure.<\/p>\n<h3 dir=\"auto\">Acute veiligheidsprofiel<\/h3>\n<ul dir=\"auto\">\n<li><strong>Hart-en vaatstelsel<\/strong>: Significant increases in heart rate (tachycardia), blood pressure (hypertension), and risk of chest pain or arrhythmias.<\/li>\n<li><strong>Neurological \/ Psychiatric<\/strong>: Agitation, anxiety, paranoia, psychosis, hallucinations, seizures, and psychomotor agitation are commonly reported in intoxications.<\/li>\n<li><strong>Ander<\/strong>: Hyperthermia (elevated body temperature), sweating, bruxism (teeth grinding), vasoconstriction, tachypnea (rapid breathing), and insomnia.<\/li>\n<\/ul>\n<p dir=\"auto\">Animal studies show dose-dependent locomotor stimulation, hypothermia or temperature dysregulation, and sensorimotor alterations at higher doses. Human case reports describe symptoms including aggression, confusion, cardiac issues, and thoracic pain.<\/p>\n<h3 dir=\"auto\">Toxicity &amp; Reported Harms<\/h3>\n<ul dir=\"auto\">\n<li>Multiple non-fatal hospitalizations and at least <strong>10 deaths<\/strong> linked to 3-CMC (reported in Poland and Sweden between 2019\u20132021), some involving 3-CMC alone.<\/li>\n<li>High potential for <strong>compulsive redosing<\/strong> due to strong cravings, increasing overdose risk.<\/li>\n<li><strong>Neurotoxiciteit<\/strong>: Suspected dopaminergic and serotonergic toxicity similar to other cathinones (limited direct human data).<\/li>\n<li><strong>Organ risks<\/strong>: Potential cardiotoxicity, renal strain, and hepatotoxicity with heavy use.<\/li>\n<\/ul>\n<p dir=\"auto\"><strong>220mg<\/strong> significantly exceeds common recreational doses and raises the likelihood of severe adverse effects, including excited delirium, seizures, or cardiovascular complications.<\/p>\n<h3 dir=\"auto\">Geneesmiddelinteracties en contra-indicaties<\/h3>\n<ul dir=\"auto\">\n<li><strong>Hoog risico<\/strong>: Other stimulants, MDMA, cocaine, alcohol, or MAOIs (increased risk of serotonin syndrome, overheating, or cardiovascular events).<\/li>\n<li>Strongly contraindicated for individuals with heart conditions, hypertension, anxiety\/psychosis history, or mental health disorders.<\/li>\n<\/ul>\n<h3 dir=\"auto\">Product-Related Risks<\/h3>\n<p dir=\"auto\">Unregulated capsules may have inconsistent dosing, purity issues, or contain other substances. Effects can vary widely between batches.<\/p>\n<h3 dir=\"auto\">Juridische status (vanaf 2026)<\/h3>\n<p dir=\"auto\">3-CMC is controlled across the European Union, UK (Class B), and many other countries. It is banned or heavily restricted in most jurisdictions worldwide due to its harm potential.<\/p>\n<p dir=\"auto\"><strong>Belangrijke Opmerking<\/strong>: This is a neutral, educational overview based on available scientific reports, risk assessments (EMCDDA, WHO), and case data. There are <strong>very limited clinical safety studies<\/strong> on 3-CMC in humans, and significant uncertainties remain regarding both short- and long-term risks. This information does <strong>niet<\/strong> encourage use. Synthetic cathinones like 3-CMC carry substantial potential for harm, dependence, and acute toxicity. Consult a qualified healthcare professional for any health concerns and comply with all local laws.<\/p>\n\n    <div class=\"xs_social_share_widget xs_share_url after_content \t\tmain_content  wslu-style-1 wslu-share-box-shaped wslu-fill-colored wslu-none wslu-share-horizontal wslu-theme-font-no wslu-main_content\">\n\n\t\t\n        <ul>\n\t\t\t        <\/ul>\n    <\/div>","protected":false},"excerpt":{"rendered":"<p>3-CMC Capsules 220mg 3-CMC Capsules 220mg (also known as clophedrone) is a synthetic cathinone and novel psychoactive substance (NPS) belonging to the substituted cathinone class. It is not approved for any medical use and is sold primarily as a research chemical. A 220mg capsule is considered a very high \/ heavy dose according to anecdotal &hellip; <a href=\"https:\/\/trusthillpharmacy.de\/nl\/shop\/3-cmc-capsules-220mg\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">3-CMC Capsules 220mg<\/span><\/a><\/p>","protected":false},"featured_media":8473,"comment_status":"closed","ping_status":"closed","template":"","meta":{"postBodyCss":"","postBodyMargin":[],"postBodyPadding":[],"postBodyBackground":{"backgroundType":"classic","gradient":""}},"product_brand":[],"product_cat":[15],"product_tag":[284],"class_list":["post-8515","product","type-product","status-publish","has-post-thumbnail","product_cat-uncategorized","product_tag-3-cmc-capsules-220mg","instock","shipping-taxable","purchasable","product-type-variable"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.5 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>3-CMC Capsules 220mg - Trusthill Pharmacy<\/title>\n<meta name=\"description\" content=\"3-CMC Capsules 220mg (also known as clophedrone) is a synthetic cathinone and novel psychoactive substance belonging to the substituted cathinone class.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/trusthillpharmacy.de\/nl\/shop\/3-cmc-capsules-220mg\/\" \/>\n<meta property=\"og:locale\" content=\"nl_NL\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"3-CMC Capsules 220mg\" \/>\n<meta property=\"og:description\" content=\"3-CMC Capsules 220mg (also known as clophedrone) is a synthetic cathinone and novel psychoactive substance belonging to the substituted cathinone class.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/trusthillpharmacy.de\/nl\/shop\/3-cmc-capsules-220mg\/\" \/>\n<meta property=\"og:site_name\" content=\"Trusthill Pharmacy\" \/>\n<meta property=\"article:modified_time\" content=\"2026-05-25T20:48:13+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/trusthillpharmacy.de\/wp-content\/uploads\/2026\/05\/photo_4918286807682715651_y.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1070\" \/>\n\t<meta property=\"og:image:height\" content=\"1280\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Geschatte leestijd\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minuten\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/trusthillpharmacy.de\\\/shop\\\/3-cmc-capsules-220mg\\\/\",\"url\":\"https:\\\/\\\/trusthillpharmacy.de\\\/shop\\\/3-cmc-capsules-220mg\\\/\",\"name\":\"3-CMC Capsules 220mg - 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