Atarax 25mg is a brand name for hydroxyzine hydrochloride, a first-generation antihistamine with anxiolytic (anti-anxiety), sedative, and antiemetic (anti-nausea) properties. The 25 mg tablet is a common dosage form, typically white, film-coated, and scored for easy splitting. It’s available by prescription in many countries.

Primary Uses

• Anxiety and tension: Short-term relief of anxiety symptoms (e.g., 25–100 mg/day, divided doses).
• Allergic conditions: Itching, hives, dermatitis (25–100 mg/day).
• Sedation: Pre- and post-operative sedation, or as a sleep aid (25–100 mg at bedtime).
• Nausea/vomiting: Adjunct treatment Atarax 25mg.
• Off-label: Sometimes used for alcohol withdrawal or as an antipruritic (anti-itch) agent.

Dosage Guidelines (Adults, unless specified)

Always follow your doctor’s prescription. Do not exceed recommended doses.

How It Works
Hydroxyzine blocks H1 histamine receptors (reducing allergy symptoms) and has central nervous system depressant effects via antagonism of serotonin and acetylcholine receptors, leading to sedation and anxiety relief. Onset: 15–30 minutes (oral); peak effect: 1–2 hours; duration: 4–6 hours.

Side Effects

• Warnings: Avoid alcohol, driving, or operating machinery due to sedation. Not for long-term anxiety use (risk of tolerance). Contraindicated in glaucoma, prostate hypertrophy, or early pregnancy.

Evidence & Facts

• FDA-approved since 1955; generic hydroxyzine widely available.
• Studies (e.g., J Clin Psychiatry 1982) show efficacy comparable to benzodiazepines for short-term anxiety but with less abuse potential.
• Half-life: 20 hours (longer in elderly/liver impairment). Metabolized by liver; excreted via urine.
• Overdose: Can cause severe CNS depression; treated supportively (activated charcoal, monitoring).

Interactions

• Major: CNS depressants (e.g., opioids, benzos, alcohol) → enhanced sedation.
• Moderate: QT-prolonging drugs (e.g., certain antibiotics, antipsychotics).
• Check with tools like Drugs.com interaction checker.

Availability & Cost
Prescription-only. Generic ~$0.10–$0.50 per 25 mg tablet (US, 30-count).

Disclaimer: This is general information from sources like FDA labels, Lexicomp, and PubMed—not medical advice. Consult a healthcare provider for personalized guidance, especially if pregnant, breastfeeding, or on other meds. If experiencing side effects or overdose, Atarax 25mg seek emergency help immediately.